Best Enzyme Cleaner for Couch: Top Picks to Remove Stains Effectively

Last Updated on December 6, 2025 by Cassie Moorhead

Choosing the best enzyme cleaner for your couch helps remove stains and odors effectively. Enzyme cleaners break down organic messes, making cleaning easier and safer.

Couches often face spills, pet stains, and odors that regular cleaners can’t fully remove. Enzyme cleaners use natural bacteria to digest stains and odors at the source. This makes them ideal for fabric couches and upholstery. Products like Zeiff Pro-Grade, Rocco & Roxie Oxy, FAVIRZCE, and NOYATECH offer strong, safe cleaning options.

They work on pet stains, food spills, and tough odors without harsh chemicals. These cleaners also dry quickly and are safe for families and pets. Choosing the right enzyme cleaner keeps your couch fresh and extends its life. This guide will help you find the top enzyme cleaner for your needs.

Zeiff Pro-grade Multi-purpose Probiotic Enzyme Cleaner

The Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner is ideal for pet owners, homeowners, and professionals seeking a powerful yet safe solution for stubborn stains and odors. If you’re looking for an effective cleaner that tackles pet stains, eliminates odors, and can also be used as a drain cleaner, this product is designed for you. Its probiotic enzyme formula makes it perfect for anyone who values eco-friendly and non-toxic cleaning options suitable for various surfaces.

Pros:

• Contains a probiotic enzyme formula that naturally breaks down stains and odors
• Multi-purpose use: effective on pet stains, odors, and even drains
• Safe for professional and home surfaces, making it versatile
• Fresh Breeze scent leaves a pleasant, lasting fragrance
• Convenient 32-ounce size with easy-to-use packaging

Cons:

• May require multiple applications for extremely stubborn stains
• Some users may prefer a scent-free option

The Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner features a specialized enzyme blend that effectively targets organic stains and odors, especially those caused by pets. This means it doesn’t just mask odors but eliminates them at the source, providing a deeper clean. The inclusion of probiotics supports continuous cleanliness by balancing the microbial environment on surfaces, which helps prevent reoccurring smells and buildup.

Its versatility is another standout feature, suitable for various surfaces including carpets, upholstery, hard floors, and even drains. The product’s professional-grade strength ensures that users benefit from a reliable cleaning experience whether at home or in commercial settings. Additionally, the fresh breeze scent enhances the cleaning process by leaving behind a refreshing aroma, making your space not only clean but inviting.

To buy this product, click here.

Rocco & Roxie Oxy Stain Remover

The Rocco & Roxie Oxy Stain Remover is ideal for pet owners and anyone dealing with stubborn stains on various surfaces. Whether you have carpets, upholstery, couches, or even car seats that need a thorough cleaning, this oxygen-powered carpet cleaner spray is designed to tackle tough pet stains effectively. It’s perfect for those seeking a versatile, powerful, and easy-to-use spot cleaner for multiple household fabrics and materials.

Pros:

• Powerful oxygen-based formula for deep stain removal
• Safe to use on multiple surfaces including carpet, upholstery, rugs, and clothes
• Effective against tough pet stains and odors
• Easy-to-use spray bottle design
• Non-toxic and environmentally friendly ingredients

Cons:

• May require multiple applications on very old or set-in stains
• Not suitable for delicate fabrics without prior testing
• Heavier bottle (2.0 pounds) may be less convenient for travel

The Rocco & Roxie Oxy Stain Remover offers a robust cleaning solution powered by oxygen to break down and lift stains from deep within fibers. This means users benefit from a thorough clean that not only removes visible marks but also neutralizes odors, making it especially valuable for pet owners. Its compatibility with a wide range of surfaces, including carpets, couches, rugs, and even laundry, adds to its versatility and convenience.

Additionally, the product’s user-friendly design and safe formulation ensure that it can be used frequently without worry about harsh chemicals damaging fabrics or harming household members. With dimensions of 10 inches in height and weighing 2.0 pounds, it provides a solid amount of cleaner for regular use, making it a reliable tool in maintaining a fresh, stain-free home environment.

To buy this product, click here.

Zeiff Pro-grade Multi-purpose Probiotic Enzyme Cleaner

The Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner is ideal for both professional cleaners and homeowners seeking a powerful yet gentle cleaning solution. If you want an effective cleaner that tackles tough stains and odors without harsh chemicals or fragrances, this product is perfect for you. It is especially suited for those who prefer eco-friendly and safe cleaning options for a variety of surfaces.

Pros:

• Contains probiotic enzymes that break down dirt and grime efficiently
• Multi-purpose formula suitable for various professional and home surfaces
• Odor eliminating properties to leave spaces fresh and clean
• Fragrance-free, making it ideal for sensitive individuals
• Large 32-ounce bottle offers extended use

Cons:

• May require multiple applications for extremely tough stains
• Fragrance-free formula might feel less refreshing compared to scented cleaners

The Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner features an advanced probiotic enzyme formula designed to actively break down organic matter, grease, and grime. This ensures a thorough clean without the need for harsh chemicals, which makes it safer for use around children and pets. Its multi-surface compatibility means you can confidently use it on countertops, floors, upholstery, and other professional or home surfaces without damage.

Beyond cleaning, the product excels in eliminating odors at the source, thanks to its probiotic action, which helps maintain a fresh environment. Being fragrance-free adds to its appeal for those sensitive to strong smells or allergies. The large 32-ounce size ensures you have an ample supply for regular cleaning tasks, making it a cost-effective and reliable choice for long-term use.

To buy this product, click here.

Favirzce Couch Cleaner & Stain Remover Spray

The FAVIRZCE Couch Cleaner & Stain Remover Spray is ideal for homeowners, pet owners, and anyone looking to maintain the cleanliness of their fabric sofas, carpets, furniture, couches, and car interiors. If you want a powerful, pet-safe, and non-toxic cleaning solution that quickly dries and effectively removes stains, this product is perfect for you.

Pros:

• Effective multi-surface upholstery cleaner suitable for fabric sofas, carpets, furniture, couches, and car interiors
• Pet-safe and non-toxic formula ensuring safety around pets and children
• Quick-drying spray that saves time and prevents moisture damage
• Easy to use spray bottle for convenient application
• Produced by the trusted FAVIRZCE brand and manufacturer

Cons:

• May require multiple applications for very stubborn stains
• Not suitable for leather or non-fabric surfaces

The FAVIRZCE Couch Cleaner & Stain Remover Spray stands out with its strength and versatility as a multi-surface upholstery cleaner. Designed to target tough stains, it works effectively on a variety of fabric surfaces including sofas, carpets, and car interiors. This makes it a comprehensive solution for keeping your living and vehicle spaces spotless without the need for multiple cleaners.

Beyond its cleaning power, the spray is formulated to be pet-safe and non-toxic, offering peace of mind to households with pets and children. Its quick-drying property enhances convenience, allowing users to clean surfaces without worrying about lingering dampness or damage. Overall, this product combines safety, efficiency, and ease of use, making it an excellent choice for fabric upholstery maintenance.

To buy this product, click here.

Noyatech Couch Cleaner And Stain Remover Spray

The NOYATECH Couch Cleaner and Stain Remover Spray is ideal for homeowners, pet owners, and car enthusiasts who want a reliable, professional-strength solution to keep their fabric and upholstery spotless and fresh. If you struggle with tough stains on your couches, sofas, or car interiors and need a pet-safe, non-toxic product that dries quickly, this cleaner is perfect for you.

Pros:

• Professional strength formula for deep cleaning and stain removal
• Safe for multiple surfaces including fabric, upholstery, and car interiors
• Pet-safe and non-toxic ingredients ensure safety around animals and children
• Quick-drying formula allows for fast use without long wait times
• Compact and lightweight design with dimensions 9.0 x 2.0 x 4.0 inches, weighing only 2.5 pounds

Cons:

• May require multiple applications for extremely stubborn stains
• Limited availability in some regions or stores

The NOYATECH Couch Cleaner and Stain Remover Spray stands out with its multi-surface cleaning capability, making it versatile for use on various fabrics and upholstery types. Its professional strength formula effectively breaks down and lifts stains, including those caused by pets, food, and everyday spills. Users benefit from its quick-drying nature, which means furniture and car interiors can be used soon after cleaning without waiting hours for drying.

Beyond stain removal, this cleaner prioritizes safety by being pet-safe and non-toxic. This feature reassures pet owners that their beloved animals are not exposed to harmful chemicals during or after the cleaning process. Additionally, its compact size and lightweight design make it convenient to store and handle, whether cleaning at home or on the go, such as inside vehicles. Overall, the NOYATECH spray balances powerful cleaning performance with user and pet-friendly attributes.

To buy this product, click here.

Frequently Asked Questions

What Makes Enzyme Cleaners Effective For Couch Stains?

Enzyme cleaners break down organic stains and odors naturally. They target proteins, fats, and other compounds, ensuring deep cleaning. This process removes tough pet stains and odors effectively without harsh chemicals, making them safe for couches and upholstery.

Are Enzyme Cleaners Safe For All Couch Fabrics?

Most enzyme cleaners are safe for various fabrics, including upholstery and carpets. Always check the product label for fabric compatibility. Testing on a small hidden area is recommended before full application to avoid any potential discoloration or damage.

How Do Probiotic Enzyme Cleaners Differ From Regular Ones?

Probiotic enzyme cleaners contain live beneficial bacteria that enhance stain breakdown. They continue working over time by consuming odor-causing molecules. This makes them more effective for persistent stains and odors compared to regular enzyme cleaners.

Can Enzyme Cleaners Remove Pet Odors From Couches?

Yes, enzyme cleaners specifically target and break down pet urine and other organic odors. They eliminate the source of the smell, not just mask it. This results in a fresher and cleaner couch environment.

How Quickly Do Enzyme Cleaners Dry On Upholstery?

Most enzyme cleaners dry quickly, typically within 15 to 30 minutes. Quick-drying formulas prevent mold and mildew growth, making them ideal for couches and car interiors. Always follow product instructions for best drying times and results.

Conclusion

Choosing the right enzyme cleaner can make couch cleaning easier and more effective. The products listed offer strong stain removal and odor elimination. They work well on pet stains, food spills, and everyday dirt. Many are safe for pets and quick to dry, which helps keep your furniture fresh.

Using enzyme cleaners regularly helps maintain your couch’s look and smell. Remember to follow the instructions for best results. With these options, you can find a cleaner that fits your needs and budget. A clean couch means a healthier and more comfortable home.

Try one of these trusted enzyme cleaners and enjoy a fresher living space. Simple, safe, and powerful—these products help keep your couch looking its best.